The seat had become vacant when the constituency's Unionist Member of Parliament (MP), the Marquess of Clydesdale, succeeded to the peerage as Duke of Hamilton.
He had been East Renfrewshire's MP since winning the seat at a by-election in 1930.
During the Second World War unopposed by-elections were common, since the major parties had agreed not to contest by-elections when vacancies arose in seats held by the other parties; contests occurred only when independent candidates or minor parties chose to stand.
On a much-reduced turnout, the result was a massive victory for Lloyd, who won 80.7% of the votes.
He remained East Renfrewshire's MP until he stepped down at the 1959 election.