In their third season under head coach Frank Howard, the Tigers compiled a 3–6–1 record (2–3–1 against conference opponents), finished ninth in the conference, and were outscored by a total of 138 to 100.
[1][2] Memorial Stadium was inaugurated September 19 with a win against Presbyterian College.
Clemson's 200th win came on Big Thursday against South Carolina.
[3] End Chip Clark was selected as a first-team player on the 1942 All-Southern Conference football team.
89 (out of 590 college and military teams) in the final rankings under the Litkenhous Difference by Score System for 1942.