R Antwerp FC won their 3rd Premier Division title.

[1] The Belgium national football team did not play any official match during the season.

At the end of the season, TSV Lyra and R Tilleur FC were relegated to Division I, while Sint-Niklaas SK (Division I A winner) and RFC Liégeois (Division I B winner) were promoted to the Premier Division.

However, due to the latter stages of World War II, 4 clubs did not take part to the next Premier Division season: R Antwerp FC, R Beerschot AC, K Liersche SK and R Berchem Sport.

[2] ASV Oostende KM, K Tubantia FC, R Uccle Sport and R Fléron FC were relegated from Division I to Promotion, to be replaced by RCS Hallois, RC Lokeren, UR Namur and Beringen FC.