The seat had become vacant when the constituency's Conservative Member of Parliament (MP) Lord Apsley had been killed on 17 December 1942, whilst on active service in the Second World War.
In Bristol Central, the former ILP MP Jennie Lee stood as an "Independent labour" candidate.
The current ILP General Secretary, John McNair, also stood.
On a turnout less than half of that in the 1935 general election, Lady Apsley held the seat with a slightly increased majority.
This article about a by-election to the Parliament of the United Kingdom in England is a stub.