It began on 18 February 1945 with the quarterfinals and concluded on 15 April 1945 with the final which was held at GSP Stadium.
EPA won their 1st Cypriot Cup trophy after beating APOEL 3–1 in the final.
In all rounds each tie was played as a single leg and was held at the home ground of one of the two teams, according to the draw results.
If a match was drawn, extra time was following.
If extra time was drawn, there was a replay match.