The 1948–49 Cupa României was the 12th edition of Romania's most prestigious football cup competition.
The title was won by CSCA București against CSU Cluj.
In the first round proper, if a match is drawn after 90 minutes, the game goes in extra time, and if the score is still tied after 120 minutes, the team from the lower league will qualify.
In the rest of the rounds, if a match is drawn after 90 minutes, the game goes in extra time, and if the score is still tied after 120 minutes, the team who plays away will qualify.
From the first edition, the teams from Divizia A entered in competition in sixteen finals, rule which remained till today.