The 1949–50 National Hurling League was the 19th season of the National Hurling League.
The National Hurling League saw a major restructuring for the 1949–50 season.
Tipperary came into the season as defending champions of the 1948–49 season.
On 24 September 1950, Tipperary won the title after a 1–12 to 3–4 win over New York in the final.
It was their third league title overall and their second in succession.