The 1949 Cotton Bowl Classic was a post-season game between the SMU Mustangs and the Oregon Ducks.

They shared the Pacific Coast Conference championship with California, who they did not play that season.

For the second straight Cotton Bowl, Doak Walker started the scoring, this time with a 1-yard touchdown run.

Most notable in the game was SMU's deep punts, one by Doak Walker for 79 and one by Kyle Rote for 84, which was crucial in pinning the Ducks in their own territory.

Norm Van Brocklin threw a pass to Dick Wilkins to narrow the lead, but the kick failed, making it only 14–6.