Stanford was led by fifth-year head coach Marchmont Schwartz.
This season marked the only time that Stanford and Harvard played each other, with the Indians winning handily, 44–0.
It was Harvard's second-ever West Coast game, after their victory in 1920 Rose Bowl.
[6] A second game, to be played at Harvard Stadium, was scheduled for the 1950 season, but was canceled by Harvard to lighten what was characterized as a "far too heavy" schedule.
But although the Indians managed a 7–6 halftime lead, the Bears took control in the second half, going on to win 33–14 and securing a return to the Rose Bowl.