The 1949 West Texas State Buffaloes football team was an American football team that represented West Texas State College (now known as West Texas A&M University) in the Border Conference during the 1949 college football season.
In its third season under head coach Frank Kimbrough, the team compiled a 5–4 record (3–2 against conference opponents) and outscored opponents by a total of 249 to 170.
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