The 1950–51 La Liga season was the 20th edition of the Spanish football top division.
Defending champions Atlético Madrid achieved their fourth title, securing it with a 1–1 draw on the final matchday away to Sevilla, their direct rivals for the championship who would have taken the trophy with a win, had a 100% home record up to that point, and who won the league five years earlier in almost identical circumstances.
The two last qualified teams were directly relegated to Segunda División and teams in the 13th and 14th position joined the relegation play-offs with the second and third qualified teams of each one of the two groups of the Segunda División.
Lérida made their debut in La Liga.
The two top teams would play the next La Liga season.