In their third season under head coach Jordan Olivar, the Lions compiled a 3–6 record and were outscored by a total of 229 to 180.
Charles S. Casassa, SJ, announced that the school was discontinuing its intercollegiate football program.
[3] Loyola's president attributed the decision to the loss of several hundred students resulting from the Korean War which began in June 1950.
The Los Angeles Times wrote that other likely factors influencing Loyola's decision included concerns about overemphasis on football, rising costs, heightened competition for players, the platoon system with its demand for a greater number of players, the lack of a suitable home field, and difficulty in scheduling games with popular teams such as UCLA and USC.
Saint Mary's College of California disbanded its program after the 1950 season, and the University of San Francisco made its announcement on the same day as Loyola.