2 in the AP Poll) defeated Indiana, 53–6, before a crowd of 58,858 at Macklin Stadium in East Lansing, Michigan.
Michigan State played backups for much of the second half with a total of 50 Spartans seeing game action.
Indiana intercepted a Northwestern pass with four minutes remaining to set up the winning touchdown.
[10] On November 3, Indiana defeated Marquette, 19–13, before a crowd of approximately 21,000 at Memorial Stadium in Bloomington.
In the fourth quarter, Indiana's Arnold Steeves recovered a fumble at Marquette's 43-yard line to set up the winning touchdown.
The Buckeyes also broke the Big Ten single-game record with 465 rushing yards against the Hoosiers.
In his final college game, Purdue quarterback Len Dawson threw two touchdown passes, both caught by end Lamar Lundy.