The 1959 Florida A&M Rattlers football team was an American football team that represented Florida A&M University as a member of the Southern Intercollegiate Athletic Conference (SIAC) during the 1959 college football season.
In their 15th season under head coach Jake Gaither, the Rattlers compiled a perfect 10–0 record, including a victory over Prairie View A&M in the Orange Blossom Classic for the black college football national championship.
14 in the final UPI small college poll.
The team played its home games at Bragg Memorial Stadium in Tallahassee, Florida.
The team's statistical leaders included Clarence Childs with 537 rushing yards, Theodore Richardson with 354 passing yards, and Williams Barber with 116 receiving yards.