Among the most notable picks was center Jim Otto, who was a fixture at the position for fifteen years and was selected to the Pro Football Hall of Fame in 1980.
The AFL had no playoff rounds, only a championship game between the league's two division winners, so Oakland's third-place finish was not enough to qualify.
The Texans jumped out to an early 10–0 lead after a field goal and a touchdown pass from Cotton Davidson to Max Boydston.
In the inaugural game of what would become one of football's most intense rivalries, Frank Filchock's Denver Broncos easily defeated the Raiders on the strength of a 21-point outburst in the second quarter.
Denver opened the scoring with a short first-quarter field goal, but Oakland took the lead after a 1-yard touchdown run by J.D.
Bill Yelverton intercepted an Oakland pass and returned it 20 yards for a touchdown, giving Denver a 24–7 lead at halftime.
The two teams combined for 35 points in the first half, including a pair of touchdown passes each from Tom Flores and the Titans' Al Dorow.
New York entered the fourth quarter with a 24–14 lead, but a pair of James "Jetstream" Smith rushing touchdowns gave Oakland the narrow win.
After a week 11 bye, the Raiders met Sid Gillman's Los Angeles Chargers for the first time on November 27, 1960.
The eventual Western Division champion Chargers piled up 31 points by halftime, led by quarterback Jack Kemp.
Billy Lott ran for a touchdown in the second quarter; Charlie Hardy caught an 11-yard pass from Tom Flores in the same period.
The two squads traded field goals in the first quarter, but Oakland entered halftime with a 17–10 lead on the strength of touchdown runs by Tom Flores and Tony Teresa.