Birmingham lost in the final of the 1960–61 Inter-Cities Fairs Cup in October 1961, and only a few weeks later, were eliminated from the 1961–62 competition in the second round by Espanyol.

Twenty-five players made at least one appearance in nationally organised first-team competition, and there were eleven different goalscorers.

Forward Mike Hellawell played in all 50 first-team matches over the season (half back Malcolm Beard missed only one), and Ken Leek and Jimmy Harris finished as joint leading goalscorers with 20 goals in all competitions; Leek was top scorer in league competition with 18 goals.

In the semi-final, Birmingham had beaten Inter Milan home and away; no other English club beat them in a competitive match in the San Siro until Arsenal did so in the Champions League more than 40 years later.

In the first leg, missed chances and poor defending allowed Roma to take a two-goal lead at St Andrew's, but second-half goals from Mike Hellawell and Bryan Orritt, whose late equaliser came after Jimmy Harris's shot rebounded from the crossbar, took Birmingham into the second leg on level terms.