In their 17th year under head coach Edwin Struck, the Redbirds compiled a 5–4 record (4–2 in conference games), tied for second place in the IIAC, and were outscored by a total of 142 to 129.

[1] The team played its home games at McCormick Field in Normal, Illinois.

Schieber also led the team in total offense (577 yards) and scoring (54 points on nine touchdowns).

Halfback Ron Schieber was selected as the team's most valuable player for the 1961 season.

[13] Three Illinois State players received first-team honors on the 1961 All-IIAC football team: Bill Monken at offensive end; Tom Mackiewicz at defensive end; and Dave Babcock at defensive tackle.