The 1961 William & Mary Indians football team was an American football team that represented the College of William & Mary as a member of the Southern Conference (SoCon) during the 1961 college football season.

In their fifth season under head coach Milt Drewer, William & Mary compiled a 1–9 record (1–6 in conference games), finished in last place in the SoCon, and were outscored by a total of 279 to 125.

[2] The team played its home games at Cary Field in Williamsburg, Virginia.

[2] Three players split time at quarterback: Dan Henning (30-for-86, 537 yards, five touchdowns, eight interceptions); Calvin Cox (41-for-69, 59.4%, three touchdowns, eight interceptions); and Dan Barton (14-for-33, 196 yards, no touchdowns, six interceptions).

End Ernie Phillips, tackle John Sapinsky, and back Roger Hale were named to the second team.