The 1965 All-Ireland Senior Hurling Championship was the 79th staging of the All-Ireland hurling championship since its establishment by the Gaelic Athletic Association in 1887.
The championship began on 25 April 1965 and ended on 5 September 1965.
Tipperary were the defending champions, and retained their All-Ireland crown following a 2-16 to 0-10 defeat of Wexford.
It was the team's fourth All-Ireland championship in five years.
A total of thirteen teams contested the championship, the same number and makeup of participants from the previous championship.