The 1972–73 Segunda División was the 24th season of the Mexican Segunda División.
The season started on 26 November 1972 and concluded on 5 July 1973.
It was won by Ciudad Madero.
[1] As of this season, the promotion playoff was established between the Second and Third Division.
The penultimate and antepenultimate classified of this category had to play a series against the second and third place of the Third Division.