The 1972 Italian Open was a combined men's and women's tennis tournament that was played by men on outdoor clay courts at the Foro Italico in Rome, Italy.

The men's and women's tournament were part of the 1972 Commercial Union Assurance Grand Prix.

The singles titles were won by Manuel Orantes and Linda Tuero.

[3] Manuel Orantes defeated Jan Kodeš 4–6, 6–1, 7–5, 6–2 Linda Tuero defeated Olga Morozova 6–4, 6–3 Ilie Năstase / Ion Țiriac defeated Lew Hoad / Frew McMillan 3–6, 3–6, 6–4, 6–3, 5–3, ret.

Lesley Hunt / Olga Morozova defeated Gail Chanfreau / Rosalba Vido 6–3, 6–4