The 1972 Pacific Southwest Open was a men's tennis tournament played on outdoor hard courts at the Los Angeles Tennis Center in Los Angeles, California in the United States.

The tournament was classified as Grade A and was part of the Grand Prix tennis circuit.

It was the 46th edition of the tournament and ran from September 18 through September 24, 1972.

[3] Third-seeded Stan Smith won the singles title.

[4][5] Stan Smith defeated Roscoe Tanner 6–4, 6–4 Jimmy Connors / Pancho Gonzales defeated Ismail El Shafei / Brian Fairlie 6–3, 7–6