The 1972 Wyoming Cowboys football team represented the University of Wyoming as a member of the Western Athletic Conference (WAC) during the 1972 NCAA University Division football season.
Led by second-year head coach Fritz Shurmur, the Cowboys compiled a record of 4–7 (3–4 against conference opponents), placing fifth in the WAC.
The team played home games on campus at War Memorial Stadium in Laramie, Wyoming.
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