1977–78 Northern Premier League

The following club left the League at the end of the previous season: The following club joined the League at the start of the season: Between Champions of NPL Premier Division and Winners of the NPL Cup.

Out of the twenty-four clubs from the Northern Premier League, only two teams reached the second round: Second Round Third Round Out of the twenty-four clubs from the Northern Premier League, two teams reached the fourth round: Fourth Round Semi-finals Final At the end of the tenth season of the Northern Premier League, Wigan Athletic who was put forward for election, received enough votes, on the second round of voting, to be promoted to the Football League.

Great Harwood folded Great Harwood Town replaced in Lancashire Combination Alongside the four Football League teams facing re-election, two non-League teams, one from the Northern Premier League and the other from the Southern League, applied to be elected.

A second round was then implemented with Wigan Athletic gaining promotion, replacing Southport from the Football League as they did not receive enough votes.

Southport was subsequently relegated to the Northern Premier League.