The 1978 Florida Federal Open was a women's singles tennis tournament played on outdoor hard courts at East Lake Woodlands Country Club in Oldsmar, Florida in the United States.

The event was part of the AA[a] category of the 1978 Colgate Series.

It was the sixth edition of the tournament and was held from November 6 through November 12, 1978.

[2] Third-seeded Virginia Wade won the title and earned $14,000 first-prize money.

[2][1][3] Virginia Wade defeated Anna-Maria Fernandez 6–4, 7–6(7–1) Martina Navratilova / Anne Smith defeated Kerry Reid / Wendy Turnbull 7–6(7–4), 6–3