The 1980–81 Kansas State Wildcats men's basketball team represented Kansas State University as a member of the Big Eight Conference in the 1980–81 NCAA Division I men's basketball season.
The team was led by head coach Jack Hartman and played their home games at Ahearn Field House in Manhattan, Kansas.
The Wildcats finished second in the conference regular season standings and received a bid to the NCAA tournament as No.
9 seed San Francisco in the opening round,[2] then upset No.
4 seed Illinois to reach the regional final where they lost to North Carolina in Elite Eight, 82–68.