The 1980 Copa Libertadores de América finals was the final two-legged tie to determine the Copa Libertadores de América champion.

[1] For the first time in 18 years, a club from Argentina did not play in the Copa Libertadores final.

With the first game tied 0–0, Nacional were crowned champion after winning the second leg 1–0 with a goal by striker Waldemar Victorino, achieving their second Copa Libertadores title.

The team that accumulated the most points —two for a win, one for a draw, zero for a loss— after the two legs was crowned champion.

If the two teams were tied on points after the second leg, a playoff in a neutral would become the next tie-breaker.