The 1980 Italian Grand Prix was a Formula One motor race held on 14 September 1980 at the Autodromo Dino Ferrari in Imola, Italy.

This was the first Formula One World Championship race to be held at Imola (the circuit having hosted the non-championship Dino Ferrari Grand Prix the previous year).

Regardless, after a heavy crash in practice at the flat-out right hander before Tosa, reigning World Champion Jody Scheckter announced his retirement from the sport.

The front row of the grid was occupied by the Renaults of René Arnoux and Jean-Pierre Jabouille, although Piquet led by lap 4 and was never headed.

Behind Reutemann, Elio de Angelis finished fourth in his Lotus, with Keke Rosberg fifth in his Fittipaldi and Didier Pironi sixth in his Ligier.