Warrington won the trophy with a 26–10 victory over Second Division side Wigan.
Barrow and Whitehaven received byes into the next round.
Huyton's match against Warrington was moved to Wilderspool due to vandalism at Huyton's home ground, Alt Park.
The final was played at Knowsley Road, St Helens, with an attendance of 6,279 and gate receipts of £8,629.
[6] This was Warrington's seventh Lancashire Cup win, and their first since 1965.