The 1980 St. Louis Cardinals season was the 61st season the team was in the league.
The team matched their previous output of 5–11.
[1] The team failed to reach the playoffs for the fifth consecutive season.
[2] Front office Head coaches Offensive coaches Special teams coaches Strength and conditioning
Running backs (RB) Wide receivers (WR) Tight ends (TE) Defensive linemen (DL) Defensive backs (DB) Special teams Reserve