The 1981 NAIA World Series was a double-elimination tournament to determine the baseball champion of the National Association of Intercollegiate Athletics (NAIA).

The tournament was held at Chaparral Stadium[note 1] on the campus of Lubbock Christian College[note 2] in Lubbock, Texas, from June 2 through June 8.

The Grand Canyon Antelopes won the tournament, the team's second consecutive NAIA baseball championship.

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