The 1985 Cal Poly Mustangs football team represented California Polytechnic State University, San Luis Obispo as a member of the Western Football Conference (WFC) during the 1985 NCAA Division II football season.
Led by fourth-year head coach Jim Sanderson, Cal Poly compiled an overall record of 4–7 with a mark of 2–3 in conference play, placing fourth in the WFC.
The team was outscored by its opponents 303 to 266 for the season.
The Mustangs played home games at Mustang Stadium in San Luis Obispo, California.
[7][8] The following Cal Poly Mustang players were selected in the 1986 NFL draft.