The 1988 Critérium du Dauphiné Libéré was the 40th edition of the cycle race and was held from 31 May to 5 June 1988.

The race started in Avignon and finished in Saint-Pierre-de-Chartreuse.

[3] The race was won by Luis Herrera of the Café de Colombia team.

Fourteen teams, containing a total of 125 riders, participated in the race:[2]