The 1988 US Open was a tennis tournament played on outdoor hard courts at the USTA National Tennis Center in New York City, United States.

It was the 108th edition of the US Open and was held from August 29 to September 11, 1988.

Mats Wilander defeated Ivan Lendl 6–4, 4–6, 6–3, 5–7, 6–4 Steffi Graf defeated Gabriela Sabatini 6–3, 3–6, 6–1 Sergio Casal / Emilio Sánchez defeated Rick Leach / Jim Pugh by walkover Gigi Fernández / Robin White defeated Patty Fendick / Jill Hetherington 6–4, 6–1 Jana Novotná / Jim Pugh defeated Elizabeth Smylie / Patrick McEnroe 7–5, 6–3 Nicolás Pereira defeated Nicklas Kulti 6–1, 6–2 Carrie Cunningham defeated Rachel McQuillan 7–5, 6–3 Jonathan Stark / John Yancey defeated Massimo Boscatto / Stefano Pescosolido 7–6, 7–5 Meredith McGrath / Kimberly Po defeated Cathy Caverzasio / Laura Lapi 6–3, 6–1