The Dutch Eredivisie in the 1990–91 season was contested by 18 teams.

PSV won the championship.

The number 16 of the Eredivisie would play against relegation against the runners-up of the promotion/relegation play-offs of the Eerste Divisie.

The Eerste Divisie league champions and winner of the play-offs would replace the numbers 17 and 18 of this league directly.

SVV: remain in Eredivisie and merge with Dordrecht '90 NAC: remain in Eerste Divisie