The 1990–91 Honduran Liga Nacional season was the 25th edition of the Honduran Liga Nacional.
The format of the tournament consisted of a three round-robins followed by a 5-team playoff round.
Club Deportivo Olimpia unsuccessfully defended its 1989 title losing in a replay match to Motagua.
España won the title [1] defeating in the final C.D.
Both title holder and runner-up qualified for berths to the 1991 CONCACAF Champions' Cup.