The 1990–91 Penn State Nittany Lions basketball team represented Pennsylvania State University as a member of the Atlantic-10 Conference during the 1990–91 season.
The team was led by head coach Bruce Parkhill and played its home games at Rec Hall in University Park, Pennsylvania.
Penn State finished the season with an overall record of 21–11 (10–8 A-10).
This was Penn State's final season in the Atlantic 10.
The Nittany Lions played an independent schedule in 1991-92, then joined the Big Ten on July 1, 1992.