The Buffalo Bills entered the season as defending AFC champions, having lost Super Bowl XXV to the New York Giants.
The Bills No Huddle “K-Gun” offense, after having a breakout 1990 season, once again dominated the league by gaining an NFL leading 6,525 yards and scoring 458 points, a franchise record, and second only to Washington.
The leaders of the offense, quarterback Jim Kelly and running back Thurman Thomas, both had the best seasons of their careers.
Once again, the Bills offensive line was led by center Kent Hull along with Pro Bowl guard Jim Ritcher.
Defensive end Phil Hansen played his entire eleven-year career in Buffalo, joining the team's Wall of Fame in 2011.
The Jets clawed to a 10–3 lead late in the second; a pass-interference penalty set up a seven-yard Andre Reed touchdown catch.
Jim Kelly overcame three interceptions to toss five touchdowns (tying a Monday Night Football record), winning 35–16.
Jason Staurovsky missed two first-half field goal attempts amid periodic heavy winds at Rich Stadium.
The Dolphins fumbled three times and Dan Marino was intercepted twice as the Bills rolled to 262 rushing yards and three Jim Kelly touchdowns, winning 41–27.
Jim Kelly and Ken O'Brien were both picked off twice as the Bills clawed to a 24–13 win, overcoming four turnovers and eleven penalties (76 yards).
Amid a burgeoning feud with team owner Al Davis, Marcus Allen put up 95 all-purpose yards on 19 combined touches (16 of them rushes) and a touchdown as the Raiders led 27–14 after three quarters.
With the #1 AFC seed confirmed, the Bills started Frank Reich against the Lions, still fighting for a playoff bye with the Bears to play the 49ers on Monday Night.
Washington kept Buffalo out of the end zone, but kicker Scott Norwood kicked a 21-yard field goal to cut their deficit to 24–3.
But Buffalo's hopes of a comeback faded when Washington advanced 79 yards in 11 plays on their ensuing drive, scoring on Clark's 30-yard touchdown reception to give the Redskins a 31–10 lead with 1:24 left in the third period.
After the turnover, Washington drove to the Bills 7-yard line and increased their lead to 34–10 with Lohmiller's 25-yard field goal on the second play of the fourth quarter.
With the game almost completely out of reach, the Bills managed to respond with a 15-play, 79-yard drive to cut the score to 37–17 on a 2-yard touchdown pass from Kelly to Metzelaars.