The 1991 South Carolina Gamecocks football team represented the University of South Carolina as an independent team in the 1991 NCAA Division I-A football season, finishing with a 3–6–2 record.

Led by returning starting quarterback Bobby Fuller,[1] during a year when "if anything could go bad, it did",[1] South Carolina's three wins were its fewest since 1986.

[2] In the season-opener against Duke at home, the Gamecocks were up by two scores near the end of the fourth quarter, but the Blue Devils scored fourteen points in the final seventy seconds to tie the game.

[2] [15] Bobby Fuller* QB Wright Mitchell QB Brandon Bennett* RB Leroy Jeter* RB Rob DeBoer RB Terry Wilburn RB Albert Haynes RB Eddie Miller* WR Robert Brooks* WR David Pitchko WR Asim Penny WR Bralyn Bennett WR Bill Zorr WR Darren Greene WR Mike Whitman* TE Matthew Campbell TE Boomer Foster TE Roderick Howell TE Mathew Campbell TE Ernest Dye* OL Kenny Farrell* OL Jay Killen* OL Antoine Rivens* OL Rich Sweet* OL Vincent Dinkins OL Kevin Rosenkrans OL Cedric Bembery* DL Bobby Brown* DL Marty Dye* DL Troy Duke DL David Turnipseed DL Ernest Dixon* LB Eric Brown* LB Gerald Dixon* LB Robert Gibson* LB Keith Franklin LB Joe Reaves LB Keith Emmons LB Toby Cates* DB Jerry Inman* DB Bru Pender* DB Tony Watkins* DB Frank Adams DB Cedric Surratt DB Norman Greene DB Daren Parker P Harold Staley LS

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