The 1992–93 Southern Illinois Salukis men's basketball team represented Southern Illinois University Carbondale during the 1992–93 NCAA Division I men's basketball season.
The Salukis were led by eighth-year head coach Rich Herrin and played their home games at the SIU Arena in Carbondale, Illinois as members of the Missouri Valley Conference.
The Salukis won the MVC tournament to receive an automatic bid to the NCAA tournament as No.
The Salukis fell to two-time defending champion and No.
3 seed Duke in the opening round.