The final was contested by Mexican Club Puebla (winner of 1991 CONCACAF Champions' Cup) and Chilean club Colo-Colo (champion of 1991 Copa Libertadores).

The final was played under a two-leg format in September 1992.

[1] The first leg was held in Estadio Olímpico in Villahermosa, where Colo-Colo easily beat Puebla 4–1.

The second leg was played at Estadio Monumental David Arellano in Santiago, with another Colo-Colo win over Puebla (3–1).

With two wins and a 7–2 aggregate score,[1] the Chilean side won their first Interamericana trophy.