Two-time defending champion Monica Seles defeated Steffi Graf in the final, 6–2, 3–6, 10–8 to win the women's singles tennis title at the 1992 French Open.

It was her third French Open title and sixth major title overall, becoming the first woman in the Open Era to win three consecutive French Open titles.

The final is considered by some to be the greatest French Open match in the Open Era.

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