The 1993 Southern Illinois Salukis football team represented Southern Illinois University as a member of the Gateway Football Conference during the 1993 NCAA Division I-AA football season.
They were led by fifth-year head coach Bob Smith and played their home games at McAndrew Stadium in Carbondale, Illinois.
The Salukis finished the season with a 2–9 record overall and a 1–5 record in conference play.
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