Running backs (RB) Wide receivers (WR) Tight ends (TE) Defensive linemen (DL) Defensive backs (DB) Special teams Reserve Note: Intra-division opponents are in bold text.

On the opening kickoff, Colts return specialist Aaron Bailey, found a gap and sprinted 95 yards for a touchdown.

The Jaguars countered by moving the ball to the Colts' 9–yard line; however, Mike Hollis' 27–yard field goal attempt was blocked.

A 45–yard completion to wide receiver Willie Jackson contributed to a Jaguars touchdown, cutting the Colts lead to 7 early in the second quarter.

On the following drive, Jaguars' quarterback Mark Brunell was intercepted by cornerback Eugene Daniel, who returned it to Jacksonville's 3–yard line.

As the fourth quarter began, the Jaguars executed a touchdown drive, reducing the Colts lead to 10.

They made a third attempt at an onside kick, but the Colts again recovered, ultimately securing a 41–31 victory in their inaugural matchup.