The 1995 SMU Mustangs football team represented Southern Methodist University (SMU) as a member of the Southwest Conference (SWC) during the 1995 NCAA Division I-A football season.
Led by fifth-year head coach Tom Rossley, the Mustangs compiled an overall record of 1–10 with a mark of 0–7 in conference play, placing last out of eight teams in the SWC.
[1] SMU returned to the Cotton Bowl on a permanent basis for the first time since 1978.
SMU opened the season with an upset over eventual Southeastern Conference (SEC) Western Division champion Arkansas, 17–14.
SMU, along with TCU and Rice, joined the Western Athletic Conference (WAC) in 1996.