The 1999–2000 FIBA Saporta Cup was the thirty-fourth edition of FIBA's 2nd-tier level European-wide professional club basketball competition.

The final was held at Lausanne, Switzerland.

For the 1999–2000 FIBA Saporta Cup, the countries are allocated places according to their place on the FIBA country rankings, which takes into account their performance in European competitions from 1996–97 to 1998–99.

[1] The labels in the parentheses show how each team qualified for the place of its starting round: * Tatami Rhöndorf (3rd in the previous season of Bundesliga) merged with Skyliners Frankfurt (at that time newly formed club), so Skyliners took their place in the competition.

April 11, Centre Intercommunal de Glace de Malley, Lausanne