The Newcastle Falcons folded and were replaced by the Cairns Taipans.

The 1999-2000 regular season took place over 24 rounds between 2 October 1999 and 11 March 2000.

Source: NBL.com.au The NBL tie-breaker system as outlined in the NBL Rules and Regulations states that in the case of an identical win–loss record, the results in games played between the teams will determine order of seeding.

13-way Head-to-Head between Adelaide 36ers (3-3), Townsville Crocodiles (3-3) and Perth Wildcats (3-3).

23-way Head-to-Head between Wollongong Hawks (4-2), Canberra Cannons (3-3) and Sydney Kings (2-4).