The 1999-2000 National Football League, known for sponsorship reasons as the Church & General National Football League, was the 69th staging of the National Football League (NFL), an annual Gaelic football tournament for the Gaelic Athletic Association county teams of Ireland.
Derry beat Meath in the final after a replay.
Teams earned 2 points for a win and 1 for a draw.
The bottom two teams in Divisions 1A and 1B were relegated.
The top two teams in Divisions 1A and 1B progressed to the NFL semi-finals.