The 1999–2000 Purdue Boilermakers men's basketball team represented Purdue University as a member of the Big Ten Conference during the 1999–2000 NCAA Division I men's basketball season.

The team was led by Gene Keady and played its home games at Mackey Arena.

[2] During the 2000 NCAA Division I men's basketball tournament, Purdue qualified for the Elite Eight, where they lost to the Wisconsin Badgers.

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