The 1999–2000 Slovak Cup was the 31st season of Slovakia's annual knock-out cup competition[1] and the seventh since the independence of Slovakia.
It began on 25 July 1999 with the matches of preliminary round and ended on 8 May 2000 with the final.
The winners of the competition earned a place in the first round of the UEFA Cup.
Slovan Bratislava were the defending champions.
The first legs were played on 25 July 1999.